| Chemical Properties | Back Directory | [Melting point ]
182-183 °C | [Boiling point ]
338.4±25.0 °C(Predicted) | [density ]
1.310±0.06 g/cm3(Predicted) | [storage temp. ]
-20°C | [solubility ]
DMF: 1 mg/mL,DMSO: 1 mg/mL,PBS (pH 7.2): 0.16 mg/mL | [form ]
A solid | [pka]
9.19±0.35(Predicted) |
| Hazard Information | Back Directory | [Uses]
N-Formyl-2-aminophenol (N-(2-hydroxyphenyl)methanamide) is a bacterial secondary metabolite that has been found in P. chrysogenum and has antioxidant activity[1]. | [Biological Activity]
N-formyl-2-Aminophenol is a bacterial secondary metabolite that has been found in P. chrysogenum and has antioxidant activity.1,2 It scavenges DPPH radicals in a cell-free assay with an IC50 value of 3.23 μg/ml.2 N-formyl-2-Aminophenol has also been used in the synthesis of compounds with antibacterial and antifungal activities.3 | [References]
1.Frisvad, J.C., Smedsgaard, J., Larsen, T.O., et al.Mycotoxins, drugs and other extrolites produced by species in Penicillium subgenus PenicilliumStud. Mycol.49201-241(2004)
2.Deepali, A., Akansha, A., Anamika, B., et al.Hydroxylamine hydrochloride as an effective catalyst for form amide derivative synthesis and their DPPH scavenging activityRes. J. Chem. Sci.4(10)54-57(2014)
3.Gupta, S., Verma, P., and Singh, V.Synthesis and antimicrobial study of 2-amino-imidazole derivativesIndian J. Chem. 57B679-686(2018)
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Merck KGaA
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21-20338288 |
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www.sigmaaldrich.cn |
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