| Identification | Back Directory | [Name]
6-Oxochelerythrine | [CAS]
28342-33-8 | [Synonyms]
OXYCHELERYTHRINE
6-Oxochelerythrine
Dihydrooxochelerythrine
1,2-dimethoxy-12-methyl-[1,3]benzodioxolo[5,6-c]phenanthridin-13-one
1,2-Dimethoxy-12-methyl[1,3]benzodioxolo[5,6-c]phenanthridin-13(12H)-one | [Molecular Formula]
C21H17NO5 | [MOL File]
28342-33-8.mol | [Molecular Weight]
363.36 |
| Chemical Properties | Back Directory | [Melting point ]
194-197 °C | [Boiling point ]
615.5±55.0 °C(Predicted) | [density ]
1.361±0.06 g/cm3(Predicted) | [solubility ]
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | [form ]
Powder | [pka]
-1.58±0.20(Predicted) |
| Hazard Information | Back Directory | [Description]
Oxychelerythrine shows antifeeding activities against Tribolium castaneum adults, with the EC50 of 1932 ppm.
Oxychelerythrine shows high modulatory activity enhancing the susceptibility of the S. aureus ATCC 6538 to all the tested antibiotics from two to four-fold. | [Uses]
Oxychelerythrine is an alkaloid that can be isolated from Zanthoxylum integrifoliolum. Oxychelerythrine exhibits cytotoxicity against P-388 and HT-29 cell lines with ED50s of 3.25 and 5.48 μg/mL, respectively[1]. | [Definition]
ChEBI: 6-Oxochelerythrine is a benzophenanthridine alkaloid. | [target]
Antifection | [References]
[1] Chen, J.-J., et al. New Indolopyridoquinazoline, Benzo[c]phenanthridines and Cytotoxic Constituents fromZanthoxylum integrifoliolum . Planta Medica, 71(5), 470–475. |
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