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ChemicalBook--->CAS DataBase List--->2830555-70-7

2830555-70-7

2830555-70-7 Structure

2830555-70-7 Structure
IdentificationBack Directory
[Name]

3-[4-[(Dimethylamino)methyl]phenyl]-N-methyl-N-[5-[3-methyl-5-(1,3,5-trimethyl-1H-pyrazol-4-yl)-2-pyridinyl]-1,3,4-oxadiazol-2-yl]imidazo[1,2-a]pyridine-6-methanamine
[CAS]

2830555-70-7
[Synonyms]

AZ 14145845 New
3-[4-[(Dimethylamino)methyl]phenyl]-N-methyl-N-[5-[3-methyl-5-(1,3,5-trimethyl-1H-pyrazol-4-yl)-2-pyridinyl]-1,3,4-oxadiazol-2-yl]imidazo[1,2-a]pyridine-6-methanamine
[Molecular Formula]

C32H35N9O
[MOL File]

2830555-70-7.mol
[Molecular Weight]

561.68
Chemical PropertiesBack Directory
[density ]

1.26±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(Predicted)
[pka]

8.67±0.28(Predicted)
Hazard InformationBack Directory
[Uses]

AZ14145845 is a highly selective type I1/2 dual Mer/Axl kinase inhibitor with in vivo efficacy.
[IC 50]

Axl; Mer
[References]

[1] McCoull W, et al. Optimization of an Imidazo[1,2-a]pyridine Series to Afford Highly Selective Type I1/2 Dual Mer/Axl Kinase Inhibitors with In Vivo Efficacy. J Med Chem. 2021 Sep 23;64(18):13524-13539. DOI:10.1021/acs.jmedchem.1c00920
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