| Identification | Back Directory | [Name]
(R)-(+)-1-(4-PYRIDYL)ETHANOL | [CAS]
27854-88-2 | [Synonyms]
(1R)-1-(4-Pyridyl)ethanol
(R)-1-(pyridin-4-yl)ethanol
(R)-(+)-1-(4-PYRIDYL)ETHANOL
4-[(R)-1-Hydroxyethyl]pyridine
(R)-1-(pyridin-4-yl)ethan-1-ol
(1R)-1-(pyridin-4-yl)ethan-1-ol
(R)-4-(1-HYDROXYETHYL) PYRIDINE
(R)-α-Methylpyridine-4-methanol
(αR)-α-Methylpyridine-4-methanol
(aR)-a-Methyl-4-PyridineMethanol
4-PyridineMethanol, α-Methyl-, (R)-
(r)-(+)-α-methyl-4-pyridinemethanol
(R)-(+)-ALPHA-METHYL-4-PYRIDINEMETHANOL
(αR)-α-Methyl-4-pyridinemethanol,99%e.e.
(R)-4-(1-Hydroxyethyl)pyridine, (99+% ee)
(R)-(+)-alpha-Methyl-4-pyridinemethanol 99%
(R)-(+)-α-Methyl-4-pyridinemethanol, min. 98%
(R)-4-(1-Hydroxyethyl)pyridine,99+%,(99+% ee)
(R)-4-(1-Hydroxyethyl)pyridine, (99+% ee), 99+%
(R)-4-(1-Hydroxyethyl)pyridine(R)-(+)-1-(4-Pyridyl)ethanol
(R)-(+)-ALPHA-METHYL-4-PYRIDINEMETHANOL, 99% (98% EE/GLC) | [Molecular Formula]
C7H9NO | [MDL Number]
MFCD00077865 | [MOL File]
27854-88-2.mol | [Molecular Weight]
123.15 |
| Chemical Properties | Back Directory | [Appearance]
White needles | [Melting point ]
67-69 °C(lit.)
| [Boiling point ]
239.7±15.0 °C(Predicted) | [density ]
1.082±0.06 g/cm3(Predicted) | [storage temp. ]
2-8°C
| [solubility ]
soluble in Methanol | [form ]
Crystalline Powder or Needles | [pka]
13.52±0.20(Predicted) | [color ]
White | [Optical Rotation]
[α]20/D +55°, c = 1 in chloroform | [BRN ]
4306037 | [InChIKey]
HVOAMIOKNARIMR-ZCFIWIBFSA-N |
| Hazard Information | Back Directory | [Chemical Properties]
White needles | [Uses]
(1R)-1-(4-Pyridyl)ethanol is a building block reagent used in the synthesis of potent GPR119 receptor agonists used in the treatment of diabetes. | [Purification Methods]
Purify it by recrystallisation from pet ether. The m recorded after sublimation was 59.9-60.2o, and 55o after crystallisation from *C6H6/pet ether or pet ether/*C6H6. The (-)-di-O-benzoyl tartrate salt has m 146-148o (from EtOH). [UV, ORD: Harelli & Samori J Chem Soc Perkin Trans 2 1462 1974.] The racemate recrystallises from Et2O with m 74-76o,b 90-94o/1mm. The picrate has m 125-126o (from *C6H6). [Ferles & Attia Collect Czech Chem Commun 38 611 1973, UV, NMR: Nielson et al. J Org Chem 29 2898 1964, Beilstein 21 III/IV 522, 21/2 V 217.] |
| Questions And Answer | Back Directory | [Reaction]
- Used for the synthesis of chiral 1-(4-pyridinyl)ethylamines
- Precursor for intermediates of highly stable chiral (A)6-B Supramolecular Copolymers
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