| Chemical Properties | Back Directory | [Boiling point ]
620.750±55.00 °C(Press: 760.00 Torr)(predicted) | [density ]
1.104±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | [form ]
Solid | [pka]
16.294±0.46(predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
Skp2 inhibitor 2 (14f) is an inhibitor of F-box protein S-phase kinase-associated protein 2 (Skp2), with an IC50 value of 10.2 μM (Skp2-Cks1). Skp2 is a part of cullin-RING ligases, which recruits and ubiquitinates substrates, involving in proteolytic and non-proteolytic process[1]. |
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