| Hazard Information | Back Directory | [Uses]
PROTAC AR Degrader-6 (Compound 1) is a PROTAC androgen receptor degrader (DC50: 10 nM in VCaP cell). PROTAC AR Degrader-6 blocks the process of androgen receptor transduction and also degrades the receptor itself. PROTAC AR Degrader-6 can be used for prostate cancer research. Pink: AR ligand (HY-130845); Blue: E3 ligase ligand (HY-W1003189); Black: linker (HY-169975)[1]. | [References]
[1] Lu H.F, et al. 酞嗪酮類化合物及其制備方法和醫(yī)藥用途. China, WO2021249534 A1.2021-12-16. |
|
|