| Identification | Back Directory | [Name]
1,5-DIAMINO-3-OXAPENTANE | [CAS]
2752-17-2 | [Synonyms]
EDR 104
Amino-PEG1-Amine
Jeffamine EDR 104
2,2'-Oxydiethanamine
2,2'-OXYDIETHYLAMINE
2,2’-oxybis-ethanamin
Di(2-aminoethyl) ether
2,2'-OXYBIS(ETHYLAMINE)
BIS(2-AMINOETHYL) ETHER
2,2'-Oxybis(ethanamine)
1,5-DIAMINO-3-OXAPENTANE
3-Oxapentane-1,5-diamine
3-Oxa-1,5-pentanediamine
2,2'-DIAMINODIETHYL ETHER
2,2'-Oxybis(ethylamine),98%
2-(2-aminoethoxy)ethanamine
2-(2-Aminoethoxy)ethylamine
1,5-DIAMINO-3-OXAPENTANE 98%
2-(2-aminoethoxy)ethan-1-amine
Bis(2-aminoethyl) Ether
2,2'-Diaminodiethyl Ether
2,2'-Oxydiethylamine | [EINECS(EC#)]
220-395-5 | [Molecular Formula]
C4H12N2O | [MDL Number]
MFCD00142560 | [MOL File]
2752-17-2.mol | [Molecular Weight]
104.15 |
| Chemical Properties | Back Directory | [Appearance]
clear colorless liquid | [Boiling point ]
69-71 °C (15 mmHg)
| [density ]
0,98 g/cm3 | [vapor pressure ]
2.39hPa@20°C | [refractive index ]
1.455-1.458
| [storage temp. ]
Keep in dark place,Sealed in dry,2-8°C | [form ]
Liquid | [pka]
pK1: 8.62(+2);pK2: 9.59(+1) (30°C) | [color ]
Clear colorless | [Water Solubility ]
100g/L@20°C | [InChI]
InChI=1S/C4H12N2O/c5-1-3-7-4-2-6/h1-6H2 | [InChIKey]
GXVUZYLYWKWJIM-UHFFFAOYSA-N | [SMILES]
O(CCN)CCN | [LogP]
-2.12 at 22℃ | [CAS DataBase Reference]
2752-17-2 | [EPA Substance Registry System]
Ethanamine, 2,2'-oxybis- (2752-17-2) |
| Hazard Information | Back Directory | [Chemical Properties]
clear colorless liquid | [Description]
Amino-PEG1-Amine is a water soluble PEG linker containing two amino groups. The amino groups are reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. | [Uses]
2,2''-Oxydiethanamine is a coating resin modifier. | [Definition]
ChEBI: Diamino-poly(ethylene glycol) is a poly(ethylene glycol) terminated with -NH2 groups. It is a poly(ethylene glycol) derivative and a primary amino compound. | [Flammability and Explosibility]
Notclassified(100%) | [Synthesis]
General procedure for the synthesis of 2,2'-oxydiethylamine from 2,2'-(oxybis(ethane-2,1-diyl))bis(isoindoline-1,3-dione): the raw material (575 mg, 0.83 mmol) was mixed with 80% hydrazine hydrate (8.3 mmol) in chloroform (10 mL) with reflux stirring for 4 hours. After completion of the reaction, the reaction mixture was treated with water and extracted with chloroform. The organic layer was dried with magnesium sulfate followed by evaporation of the solvent. Purification by distillation afforded the target product 2,2'-oxy diethylamine (9a) in 93% yield; boiling point 75-79°C/5 mmHg (literature value 31: 55-60°C/2 mmHg). The structure of the product was confirmed by 1H NMR (500 MHz, DMSO-d6) δ 8.31 (4H, br s), 3.32 (4H, t, J = 5.5 Hz), 2.63 (4H, t, J = 5.5 Hz); 13C NMR (500 MHz, DMSO-d6) δ 72.7, 41.3; and mass spectrum (FAB) m/z: 105 [ M + H] for confirmation. | [References]
[1] Tetrahedron, 2016, vol. 72, # 29, p. 4258 - 4272
[2] Chemistry of Heterocyclic Compounds (New York, NY, United States), 1982, vol. 18, # 2, p. 193 - 196
[3] Khimiya Geterotsiklicheskikh Soedinenii, 1982, # 2, p. 246 - 249
[4] Journal of Organic Chemistry USSR (English Translation), 1980, vol. 16, p. 1124 - 1129
[5] Zhurnal Organicheskoi Khimii, 1980, vol. 16, # 6, p. 1301 - 1307 |
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