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HBV-IN-34 (compound 17i) is a potent HBsAg production inhibitor. HBV-IN-34 exhibits excellent in vitro anti-HBV potency, with an EC50 of 0.018 μM and 0.044 μM for HBV DNA and HBsAg, respectively[1]. | [References]
[1] Zhang L, et, al. Discovery, optimization and biological evaluation of novel HBsAg production inhibitors. Eur J Med Chem. 2023 Aug 5;256:115387. DOI:10.1016/j.ejmech.2023.115387 |
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