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ChemicalBook--->CAS DataBase List--->2702965-27-1

2702965-27-1

2702965-27-1 Structure

2702965-27-1 Structure
IdentificationBack Directory
[Name]

6K465
[CAS]

2702965-27-1
[Synonyms]

6K465
Hazard InformationBack Directory
[Uses]

6K465 is a pyrimidine-based Aurora A (AURKA) inhibitor. 6K465 can reduce the levels of c-MYC and N-MYC oncoproteins, demonstrating anticancer activity[1].
[References]

[1] Chang C P, et al. Discovery of a long half-life AURKA inhibitor to treat MYC-amplified solid tumors as a monotherapy and in combination with everolimus[J]. Molecular Cancer Therapeutics, 2024. DOI:10.1158/1535-7163.MCT-23-0602
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