| Identification | Back Directory | [Name]
2-(2-Methoxyethylthio)-3-Methylnaphthalene-1,4-dione | [CAS]
255906-59-3 | [Synonyms]
100571
VK3-OCH3
2-[(2-Methoxy)ethylthio]-3-methyl-1,4-na
2-(2-Methoxyethylthio)-3-Methylnaphthalene-1,4-dione
2-[(2-Methoxy)ethylthio]-3-methyl-1,4-naphthoquinone
2-[(2-Methoxyethyl)thio]-3-methyl-1,4-napthalenedione
1,4-Naphthalenedione, 2-[(2-methoxyethyl)thio]-3-methyl- | [EINECS(EC#)]
803-593-1 | [Molecular Formula]
C14H14O3S | [MDL Number]
MFCD22575003 | [MOL File]
255906-59-3.mol | [Molecular Weight]
262.32 |
| Chemical Properties | Back Directory | [Boiling point ]
395.2±42.0 °C(Predicted) | [density ]
1.25±0.1 g/cm3(Predicted) | [storage temp. ]
2-8°C | [solubility ]
DMSO: soluble10mg/mL (clear solution) | [form ]
powder | [color ]
light orange to dark orange |
| Hazard Information | Back Directory | [Uses]
A vitamin K3 analogue that has been shown through study to induce cytotoxicity in tumor neuroblastoma, cancerous (malignant) tissue that develops from nerve cells. | [Biological Activity]
VK3-OCH3 is an analog of Vitamin K3 (Menadione) with potent antitumor activity. It has been shown to induce G2/M arrest and apoptosis in neuroblastoma cells with much less cytotoxicity towards normal cells. VK3-OCH3 is believed to act through up-regulation of heme oxygenase (HO)-1. |
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