| Identification | Back Directory | [Name]
Lucidadiol | [CAS]
252351-95-4 | [Synonyms]
Lucidadiol
Ganoderon B
3,26-Dihydroxylanosta-8,24-dien-7-one
Lanosta-8,24-dien-7-one, 3,26-dihydroxy-, (3β,24E)- | [Molecular Formula]
C30H48O3 | [MOL File]
252351-95-4.mol | [Molecular Weight]
456.7 |
| Hazard Information | Back Directory | [Uses]
Lucidadiol is a natural compound isolated from Ganoderma lucidum. Lucidadiol exhibits acetylcholinesterase-inhibitory activity, with IC50 values of 31 μM. Lucidadiol shows antiviral activity against influenza virus type A and HSV type 1[1][2]. | [IC 50]
AChE: 31.03 μM (IC50); BChE: 156.27 μM (IC50) | [References]
[1] Iksoo Lee, et al. Selective cholinesterase inhibition by lanostane triterpenes from fruiting bodies of Ganoderma lucidum. Bioorg Med Chem Lett. 2011 Nov 1;21(21):6603-7. DOI:10.1016/j.bmcl.2011.04.042
[2] Lee I,et al. Selective cholinesterase inhibition by lanostane triterpenes from fruiting bodies of Ganoderma lucidum [published correction appears in Bioorg Med Chem Lett. 2013 Nov 15;23(22):6199-200]. Bioorg Med Chem Lett. 2011;21(21):6603-6607. DOI:10.1016/j.bmcl.2011.04.042
[3] Mothana RA,et al. Antiviral lanostanoid triterpenes from the fungus Ganoderma pfeifferi. Fitoterapia. 2003;74(1-2):177-180. DOI:10.1016/s0367-326x(02)00305-2 |
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