Identification | Back Directory | [Name]
Benzamide, 4-[(7S)-4-amino-7,8-dihydro-6-methylene-7-[(1-oxo-2-butyn-1-yl)amino]-6H-pyrimido[5,4-b]pyrrolizin-5-yl]-N-2-pyridinyl- | [CAS]
2502301-31-5 | [Synonyms]
Benzamide, 4-[(7S)-4-amino-7,8-dihydro-6-methylene-7-[(1-oxo-2-butyn-1-yl)amino]-6H-pyrimido[5,4-b]pyrrolizin-5-yl]-N-2-pyridinyl- | [Molecular Formula]
C26H21N7O2 | [MOL File]
2502301-31-5.mol | [Molecular Weight]
463.49 |
Hazard Information | Back Directory | [Uses]
BTK-IN-36 (S-016) is a BTK inhibitor, with IC50 of 0.5 nM. BTK-IN-36 can be used in cancer-related research[1]. | [IC 50]
BTK: 0.5 nM (IC50) | [References]
[1] Song PR,et al. Discovery of a novel BTK inhibitor S-016 and identification of a new strategy for the treatment of lymphomas including BTK inhibitor-resistant lymphomas. Acta Pharmacol Sin. 2024 Jun 4. DOI:10.1038/s41401-024-01311-x |
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