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Nrf2 activator-7 (Compound 12b) is a potent Nrf2 activator and significantly activates the Nrf2 signaling pathway. | [References]
[1] Abed DA, et al. Optimization of the C2 substituents on the 1,4-bis(arylsulfonamido)naphthalene-N,N'-diacetic acid scaffold for better inhibition of Keap1-Nrf2 protein-protein interaction. Eur J Med Chem. 2023 Apr 5;252:115302. DOI:10.1016/j.ejmech.2023.115302 |
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