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ChemicalBook--->CAS DataBase List--->24529-88-2

24529-88-2

24529-88-2 Structure

24529-88-2 Structure
IdentificationBack Directory
[Name]

1,2-DIOLEOYL-SN-GLYCEROL
[CAS]

24529-88-2
[Synonyms]

18:1 DG
ALN29882
Brn 1730457
1,2-SN-DIOLEIN
sn-1,2-diolein
(S)-1,2-DIOLEIN
DG(18:1/18:1/0:0)
2-di-(s)-(-)-olei
1,2-sn-Dioleylglycerol
L-Glycerol 1,2-dioleate
L-Glycerol 2,3-dioleate
sn-1,2-dioleoylglycerol
Olein, 1,2-di-, (S)-(-)-
glyceryl 1,2-sn-dioleate
1,2-DIOLEOYL-SN-GLYCEROL
(S)-GLYCEROL 1,2-DIOLEATE
(+)-L-Glycerol 1,2-dioleate
1-O,2-O-Dioleoyl-L-glycerol
(-)-D-Glycerol 1,2-dioleate
1-O,2-O-Dioleoyl-D-glycerol
1,2-DIOLEOYL-SN-GLYCEROL, >=97%
glycerol 1,2-di-(9Z-octadecenoate)
1 2-DIOLEOYL-SN-GLYCEROL AMPOULE*
1,2-BIS(O-9Z-OCTADECENOYL)-SN-GLYCEROL
1,2-DI[CIS-9-OCTADECENOYL]-SN-GLYCEROL
1,2-dioleoyl-sn-glycerol (C18:1,*(cis)-9)
(Z)-(S)-3-hydroxypropane-1,2-diyl dioleate
1-(hydroxymethyl)-1,2-ethanediylester,(s)-9-octadecenoicacid(z)
(9Z)-9-Octadecenoic acid 1,1′-[(1S)-1-(hydroxymethyl)-1,2-ethanediyl] ester
9-Octadecenoic acid (Z)-, 1-(hydroxymethyl)-1,2-ethanediyl ester, (S)- (9ci)
9-Octadecenoic acid(9Z)-, 1,1'-[(1S)-1-(hydroxymethyl)-1,2-ethanediyl] ester
(S)-1,2-Diolein, (S)-Glycerol 1,2-dioleate, 1,2-Di(cis-9-octadecenoyl)-sn-glycerol
[Molecular Formula]

C39H72O5
[MDL Number]

MFCD00148866
[MOL File]

24529-88-2.mol
[Molecular Weight]

620.99
Chemical PropertiesBack Directory
[Boiling point ]

670.8±35.0 °C(Predicted)
[density ]

0.9218 g/cm3
[storage temp. ]

-20°C
[solubility ]

DMF: >20 mg/ml; DMSO: >7 mg/ml; Ethanol: >30 mg/ml; PBS pH 7.2: >250 μg/ml
[form ]

Liquid
[pka]

13.69±0.10(Predicted)
[color ]

Colorless to light yellow
[biological source]

semisynthetic
[BRN ]

1730457
[InChIKey]

AFSHUZFNMVJNKX-LLWMBOQKSA-N
[SMILES]

[C@H](OC(=O)CCCCCCC/C=C\CCCCCCCC)(CO)COC(=O)CCCCCCC/C=C\CCCCCCCC
Safety DataBack Directory
[Safety Statements ]

22-24/25
[WGK Germany ]

3
[RTECS ]

RK1250000
[F ]

23
Hazard InformationBack Directory
[Description]

1,2-Dioleoyl-sn-glycerol is an analog of the protein kinase C-activating second messenger DAG. 1,2-Dioleoyl-sn-glycerol and 1,2-dioctanoyl-sn-glycerol are nearly equipotent in induction of the acrosome reaction in human sperm.
[Uses]

1,2-Dioleoyl-sn-glycerol is an analog of 1,3-Dioleoylglycerol (D4842100 which is used in the synthesis of amphiphilic gadolinium complexes as MRI contrast agents.
[Uses]

18:1 DG may be used:
  • in the lipid-protein overlay screen assay with Arabidopsis Rho-like GTPases recombinant protein and Arabidopsis plasma membrane H+-ATPase
  • in the preparation of the Golgi-like liposomes
  • in giant unilamellar vesicles (GUVs) preparation

[Definition]

ChEBI: A 1,2-diacyl-sn-glycerol in which the acyl groups at positions 1 and 2 are specified as oleoyl.
[General Description]

Diacylglycerol/diglyceride (DAG) is a glycerolipid, that is located at the plasma membrane. It is made up of two fatty acid chains that are covalently attached to a single glycerol molecule with the help of an ester linkage.
[Biochem/physiol Actions]

18:1 DG or 1,2-dioleoyl-sn-glycerol (DOG) fails to prevent the late fission events in the Golgi membrane. DOG is used in ferrihaem π–π tetramer aggregate preparation and β-haematin production.
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