| Chemical Properties | Back Directory | [Boiling point ]
765.5±70.0 °C(Predicted) | [density ]
1.27±0.1 g/cm3(Predicted) | [form ]
Solid | [pka]
3.93±0.10(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
BTT-266 is an antagonist forcalcium channel, through suppression of the CaVα1-AID-CaVβ3 interaction, with a Ki of 1.4 μM. BTT-266 modulates the activation of voltage-dependent CaV2.2. BTT-266 exhibits analgesic efficacy against neuropathic pain in rats model[1]. | [References]
[1] Chen X, et al., Small-molecule CaVα1?CaVβ antagonist suppresses neuronal voltage-gated calcium-channel trafficking. Proc Natl Acad Sci U S A. 2018 Nov 6;115(45):E10566-E10575. DOI:10.1073/pnas.1813157115 |
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| Company Name: |
cjbscvictory
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| Tel: |
13348960310 |
| Website: |
https://www.weikeqi-biotech.com/ |
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