| Identification | Back Directory | [Name]
Cyclobutanecarboxylic acid, 3-[2-[4-(8-chloro-4-oxo-4H-1-benzopyran-2-yl)phenoxy]ethoxy]-, trans- | [CAS]
2413192-49-9 | [Synonyms]
trans-ccc_R08
Cyclobutanecarboxylic acid, 3-[2-[4-(8-chloro-4-oxo-4H-1-benzopyran-2-yl)phenoxy]ethoxy]-, trans- | [Molecular Formula]
C22H19ClO6 | [MOL File]
2413192-49-9.mol | [Molecular Weight]
414.84 |
| Chemical Properties | Back Directory | [Boiling point ]
628.4±55.0 °C(Predicted) | [density ]
1.43±0.1 g/cm3(Predicted) | [form ]
Solid | [pka]
4.46±0.40(Predicted) | [color ]
Off-white to light yellow |
| Hazard Information | Back Directory | [Uses]
trans-ccc_R08 (compound 1-B) is a potent cccDNA (covalently closed circular DMA) inhibitor. trans-ccc_R08 inhibits HBeAg level with an IC50 value of 0.08 μM. trans-ccc_R08 has the potential for the research of Hepatitis B Virus infection (HBV)[1]. | [References]
[1] Song Feng, et al. Flavone compounds for the treatment and prophylaxis of hepatitis b virus disease. WO2020053249A1. |
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