| Identification | Back Directory | [Name]
1H-Imidazole-2-carboxylic acid, 1-[3-(dimethylamino)propyl]-5,5-di-(8Z)-8-heptadecen-1-yl-2,5-dihydro-, ethyl ester | [CAS]
2412492-06-7 | [Synonyms]
A12-lso5-2DC12
A12-Iso5-2DC18
1H-Imidazole-2-carboxylic acid, 1-[3-(dimethylamino)propyl]-5,5-di-(8Z)-8-heptadecen-1-yl-2,5-dihydro-, ethyl ester | [Molecular Formula]
C45H85N3O2 | [MOL File]
2412492-06-7.mol | [Molecular Weight]
700.19 |
| Chemical Properties | Back Directory | [Boiling point ]
717.7±60.0 °C(Predicted) | [density ]
0.92±0.1 g/cm3(Predicted) | [form ]
Liquid | [pka]
9.51±0.28(Predicted) | [color ]
Colorless to light yellow |
| Hazard Information | Back Directory | [Uses]
A12-Iso5-2DC18, an ionizable cationic lipid, is a potent mRNA delivery lipid vehicle[1]. | [References]
[1] Miao L, et al. Delivery of mRNA vaccines with heterocyclic lipids increases anti-tumor efficacy by STING-mediated immune cell activation. Nat Biotechnol. 2019 Oct;37(10):1174-1185. DOI:10.1038/s41587-019-0247-3 |
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