| Identification | Back Directory | [Name]
2,6-Piperidinedione, 3-[4-[[2-[2-(2-azidoethoxy)ethoxy]ethyl]amino]-1,3-dihydro-1-oxo-2H-isoindol-2-yl]- | [CAS]
2399455-48-0 | [Synonyms]
2,6-Piperidinedione, 3-[4-[[2-[2-(2-azidoethoxy)ethoxy]ethyl]amino]-1,3-dihydro-1-oxo-2H-isoindol-2-yl]- | [Molecular Formula]
C19H24N6O5 | [MOL File]
2399455-48-0.mol | [Molecular Weight]
416.44 |
| Hazard Information | Back Directory | [Uses]
Lenalidomide 4'-PEG2-azide is the Lenalidomide-based Cereblon ligand used in the recruitment of CRBN protein. Lenalidomide 4'-PEG2-azide can be connected to the ligand for protein by a linker to form PROTAC[1]. | [Biological Activity]
Lenalidomide 4'-PEG2-azide is a functionalized cereblon ligand for PROTAC? research and development; incorporates an E3 ligase ligand plus a PEG2 linker with terminal azide ready for conjugation to a target protein ligand. | [storage]
Store at -20°C | [References]
[1] Liu H, et al. Construction of an IMiD-based azide library as a kit for PROTAC research. Org Biomol Chem. 2021 Jan 6;19(1):166-170. DOI:10.1039/d0ob02120b |
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| Company Name: |
R&D Systems, Inc
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18003437475 18003437475 |
| Website: |
www.rndsystems.com |
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