| Chemical Properties | Back Directory | [Boiling point ]
967.4±75.0 °C(Predicted) | [density ]
1.18±0.1 g/cm3(Predicted) | [form ]
Solid | [color ]
White to off-white | [InChIKey]
VACCUKVGLYJBJU-UHFFFAOYSA-N | [SMILES]
C(ON1C(=O)CCC1=O)(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOC |
| Hazard Information | Back Directory | [Description]
m-PEG24-NHS ester is a PEG linker containing an NHS ester. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. The hydrophilic PEG spacer increases solubility in aqueous media. | [Uses]
m-PEG24-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | [IC 50]
PEGs; Alkyl/ether | [References]
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
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