| Identification | Back Directory | [Name]
2,5-Cyclohexadiene-1,4-dione, 2,3-dihydroxy-5-methyl-6-[(2E,6E)-3,7,11-trimethyl-2,6,10-dodecatrien-1-yl]- | [CAS]
2394733-97-0 | [Synonyms]
MAO-B-IN-12
2,5-Cyclohexadiene-1,4-dione, 2,3-dihydroxy-5-methyl-6-[(2E,6E)-3,7,11-trimethyl-2,6,10-dodecatrien-1-yl]- | [Molecular Formula]
C22H30O4 | [MOL File]
2394733-97-0.mol | [Molecular Weight]
358.47 |
| Hazard Information | Back Directory | [Uses]
MAO-B-IN-12 (Compound 16c) is a potent monoamine oxidase B (MAO-B) inhibitor with an IC50 of 1.3 μM. MAO-B-IN-12 shows a neuroprotective activity[1]. | [IC 50]
MAO-B: 1.3 μM (IC50) | [References]
[1] Hitoshi Kamauchi, et al. Synthesis of natural product-like polyprenylated phenols and quinones: Evaluation of their neuroprotective activities. Bioorg Med Chem. 2020 Jan 1;28(1):115156. DOI:10.1016/j.bmc.2019.115156 |
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