| Chemical Properties | Back Directory | [Boiling point ]
468.9±35.0 °C(Predicted) | [density ]
1.199±0.06 g/cm3(Predicted) | [form ]
Oil | [pka]
-0.31±0.50(Predicted) | [color ]
Light brown to brown |
| Hazard Information | Back Directory | [Uses]
CDC25B-IN-1 (compound 4a) is a potent inhibitor of cell division cycle 25B (CDC25B) phosphatase, with a Ki of 8.5 μM. CDC25B-IN-1 potently inhibits cell proliferation and colony formation, causes an increase of the G2/M phase[1]. | [References]
[1] Cerchia C, et al. Discovery of Novel Naphthylphenylketone and Naphthylphenylamine Derivatives as Cell Division Cycle 25B (CDC25B) Phosphatase Inhibitors: Design, Synthesis, Inhibition Mechanism, and in Vitro Efficacy against Melanoma Cell Lines. J Med Che DOI:10.1021/acs.jmedchem.9b00632 |
|
| Company Name: |
MedChemExpress
|
| Tel: |
021-58955995 |
| Website: |
www.medchemexpress.com |
|