Identification | Back Directory | [Name]
1,4-Naphthalenedione, 2-[(4-chlorophenyl)amino]-8-hydroxy- | [CAS]
2351883-15-1 | [Synonyms]
1,4-Naphthalenedione, 2-[(4-chlorophenyl)amino]-8-hydroxy- | [Molecular Formula]
C16H10ClNO3 | [MOL File]
2351883-15-1.mol | [Molecular Weight]
299.71 |
Chemical Properties | Back Directory | [Boiling point ]
509.7±50.0 °C(predicted) | [density ]
1.530±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted) | [pka]
6.66±0.20(predicted) |
Hazard Information | Back Directory | [Uses]
Antibiotic adjuvant 1 (compound 3e) is an antibiotic adjuvant that presents insufficient antibacterial activity (MIC > 128 μg/mL) and potentiate the activity of Cloxacillin (HY-B0466A)(66-fold) with synergistic effect[1]. | [References]
[1] Chaimae Majdi, et al. Synthesis of amino juglone derivatives with adjuvant activity against clinical isolated methicillin-resistant staphylococcus aureus strains. Bioorg Chem. 2024 Sep:150:107627. DOI:10.1016/j.bioorg.2024.107627 |
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