| Identification | Back Directory | [Name]
8-bromoguanosine triphosphate | [CAS]
23197-98-0 | [Synonyms]
8-Bromo-GTP
8-bromoguanosine triphosphate
8-Bromo-GTP (aqueous solution)
8-Bromoguanosine-5'-triphosphate sodium salt - 10 mM aqueous solution | [Molecular Formula]
C10H15BrN5O14P3 | [MOL File]
23197-98-0.mol | [Molecular Weight]
602.08 |
| Hazard Information | Back Directory | [Uses]
8-Br-GTP, a GTP analog, is a competitive FtsZ polymerization and GTPase activity (Ki of 31.8 μM) inhibitor. 8-Br-GTP can be used for nucleic acid modification[1]. | [References]
[1] Tilman L?ppchen, et al. GTP analogue inhibits polymerization and GTPase activity of the bacterial protein FtsZ without affecting its eukaryotic homologue tubulin. Biochemistry. 2005 May 31;44(21):7879-84. DOI:10.1021/bi047297o
[2] Jozef Hritz, et al. Optimization of replica exchange molecular dynamics by fast mimicking. J Chem Phys. 2007 Nov 28;127(20):204104. DOI:10.1063/1.2790427 |
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