Chemical Properties | Back Directory | [Boiling point ]
947.6±65.0 °C(predicted) | [density ]
1.217±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted) | [pka]
12.04±0.46(predicted) |
Hazard Information | Back Directory | [Uses]
NIP-22c is a novel coronavirus 3CLpro inhibitor. The EC50 for Verona, Calu3, Caco2 and HBTEC-ALI were 4.6, 1.1, 0.1 and 0.6 μM, respectively. NIP-22c has antiviral activity[1]. | [References]
[1] Amblard F, et al. Synthesis and biological evaluation of novel peptidomimetic inhibitors of the coronavirus 3C-like protease. Eur J Med Chem. 2024 Feb 24;268:116263. DOI:10.1016/j.ejmech.2024.116263 |
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