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ChemicalBook--->CAS DataBase List--->2304-80-5

2304-80-5

2304-80-5 Structure

2304-80-5 Structure
IdentificationBack Directory
[Name]

C18 Dihydroceramide
[CAS]

2304-80-5
[Synonyms]

C18 Dihydroceramide (d18:0/18:0)
N-[(1S,2R)-2-Hydroxy-1-(hydroxyMethyl)heptadecyl]octadecanaMide
[Molecular Formula]

C36H73NO3
[MDL Number]

MFCD01076443
[MOL File]

2304-80-5.mol
[Molecular Weight]

567.977
Chemical PropertiesBack Directory
[Appearance]

White Crystalline Solid
[Melting point ]

104-106°C
[Boiling point ]

694.8±45.0 °C(Predicted)
[density ]

0.909±0.06 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

DMSO: Soluble; Ethanol: Warmed
[form ]

A crystalline solid
[pka]

14.30±0.20(Predicted)
[color ]

White to off-white
Hazard InformationBack Directory
[Chemical Properties]

White Crystalline Solid
[Uses]

C18 Dihydroceramide can be used for ceramide composition with repairing function and cosmetic.
[Definition]

ChEBI: N-octodecanoylsphinganine is a dihydroceramide in which the ceramide N-acyl group is specified as octadecanoyl (stearoyl). It has a role as a mouse metabolite. It is a N-acylsphinganine and a N-stearoyl-sphingoid base. It is functionally related to an octadecanoic acid.
[Biological Activity]

Dihydroceramides act as precursors for ceramides in the mammalian de-novo sphingolipid pathway. vitamin D supplementation increases plasma C18 dihydroceramide (C18-DHC) levels in type 2 diabetes mellitus (T2D) patients. Low serum concentration of C18-DHC has been observed in patients with history of graft rejection and ischemic type biliary lesions (ITBL). Thereforeit can be used as a predictor of graft rejection.
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