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ChemicalBook--->CAS DataBase List--->2279068-37-8

2279068-37-8

2279068-37-8 Structure

2279068-37-8 Structure
IdentificationBack Directory
[Name]

Polatuzumab
[CAS]

2279068-37-8
[Synonyms]

Polatuzumab
Polatuzumab (anti-CD79b)
Chemical PropertiesBack Directory
[form ]

Liquid
[color ]

Colorless to light yellow
Hazard InformationBack Directory
[Uses]

Polatuzumab is a monoclonal antibody that targets CD79b on the surface of B cells. Polatuzumab can be used to synthesize the ADC Polatuzumab Vedotin (HY-132253), which has anti-tumor activity[1].
[References]

[1] Estelle Bourbon, et al. Polatuzumab vedotin: an investigational anti-CD79b antibody drug conjugate for the treatment of diffuse large B-cell lymphoma. Expert Opin Investig Drugs. 2020 Oct;29(10):1079-1088. DOI:10.1080/13543784.2020.1800638
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