Identification | Back Directory | [Name]
DS-88790512) | [CAS]
2231089-95-3 | [Synonyms]
DS-88790512) DS88790512
(DS 88790512 DS88790512 hydrochloride
(DS 88790512 | [Molecular Formula]
C22H29N3O2 | [MDL Number]
MFCD31813668 | [MOL File]
2231089-95-3.mol | [Molecular Weight]
367.48 |
Hazard Information | Back Directory | [Uses]
DS88790512 is a potent, selective, and orally bioavailable TRPC6 inhibitor with an IC50 of 11 nM. | [References]
[1] Motoyama K, et al. Discovery of a bicyclo[4.3.0]nonane derivative DS88790512 as a potent, selective, and orally bioavailable blocker of transient receptor potential canonical 6 (TRPC6). Bioorg Med Chem Lett. 2018 Jul 1;28(12):2222-2227. DOI:10.1016/j.bmcl.2018.03.056 |
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