| Identification | Back Directory | [Name]
JV-1-38 | [CAS]
221377-79-3 | [Synonyms]
JV-1-38
JV-1-38, (Phenylac-Tyr1,D-Arg2,p-chloro-Phe6,HoMoarg9,Tyr(Me)10,Abu15,Nle27,D-Arg28,HoMoarg29)-SerMorelin
(PHENYLAC-TYR1,D-ARG2,PHE(4-CL)PHE6,HOARG9,TYR(ME)10,ABU15,NLE27,D-ARG28,HOARG29)-GRF (1-29) AMIDE (HUMAN)
(Phenylac-Tyr1,D-Arg2,Phe(4-Cl)6,Homoarg9,Tyr(Me)10,Abu15,Nle27,D-Arg28,Homoarg29)-GRF (1-29) amide (human)
(PHENYLAC-TYR1,D-ARG2,P-CHLORO-PHE6,HOMOARG9,TYR(ME)10,ABU15,NLE27,D-ARG28,HOMOARG29)-GRF (1-29) AMIDE (HUMAN)
(PHENYLAC-TYR1,D-ARG2,P-CHLORO-PHE6,HOMOARG9,TYR(ME)10,ABU15,NLE27,D-ARG28,HOMOARG29)-GROWTH HORMONE-RELEASING FACTOR (1-29) AMIDE (HUMAN)
PHENYLAC-TYR-D-ARG-ASP-ALA-ILE-PHE(4-CL)-THR-ASN-HOARG-TYR(ME)-ARG-LYS-VAL-LEU-ABU-GLN-LEU-SER-ALA-ARG-LYS-LEU-LEU-GLN-ASP-ILE-NLE-D-ARG-HOARG-NH2
Phenylac-Tyr-D-Arg-Asp-Ala-Ile-p-chloro-Phe-Thr-Asn-HoMoarg-Tyr(Me)-Arg-Lys-Val-Leu-Abu-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Nle-D-Arg-HoMoarg-NH2 | [MDL Number]
MFCD02688528 |
| Chemical Properties | Back Directory | [storage temp. ]
-15°C | [Sequence]
{N-(2-phenylacetyl)}-Tyr-{d-Arg}-Asp-Ala-Ile-{4-Cl-Phe}-Thr-Asn-{Har}-{Tyr(Me)}-Arg-Lys-Val-Leu-{Abu}-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-{Nle}-{d-Arg}-{Har}-NH2 |
| Hazard Information | Back Directory | [Uses]
JV-1-36 is a growth hormone-releasing hormone (GHRH) antagonist. JV-1-36 inhibits the production of reactive oxygen species in A549 lung cancer cells. JV-1-36 can be used to study the effect of GHRH antagonists in vitro [1]. | [References]
[1] Kubra KT, et al. Growth Hormone-Releasing Hormone Antagonist JV-1-36 Suppresses Reactive Oxygen Species Generation in A549 Lung Cancer Cells. Endocrines. 2022 Dec;3(4):813-820. DOI:10.3390/endocrines3040067 |
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