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ChemicalBook--->CAS DataBase List--->2205-73-4

2205-73-4

2205-73-4 Structure

2205-73-4 Structure
IdentificationBack Directory
[Name]

tiomesterone
[CAS]

2205-73-4
[Synonyms]

STA-307
tiomesterone
Thiomesterone
YUOZKOLALXNELS-SQVYRKCQSA-N
1α,7α-Bis(acetylthio)-17β-hydroxy-17α-methylandrost-4-en-3-one
1α,7α-Bis(acetylthio)-17β-hydroxy-17α-methylandrost-4-ene-3-one
Androst-4-en-3-one, 1,7-bis(acetylthio)-17-hydroxy-17-methyl-, (1α,7α,17β)-
S-[(1S,7R,8S,9S,10R,13S,14S,17S)-1-acetylsulfanyl-17-hydroxy-10,13,17-trimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-7-yl] ethanethioate
S-[(1S,7R,8S,9S,10R,13S,14S,17S)-1-ethanoylsulfanyl-17-hydroxy-10,13,17-trimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-7-yl] ethanethioate
ethanethioic acid S-[(1S,7R,8S,9S,10R,13S,14S,17S)-1-(acetylthio)-17-hydroxy-3-keto-10,13,17-trimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-7-yl] ester
[EINECS(EC#)]

218-614-4
[Molecular Formula]

C24H34O4S2
[MOL File]

2205-73-4.mol
[Molecular Weight]

450.65
Chemical PropertiesBack Directory
[Melting point ]

205-206°
[alpha ]

D -66° (dioxane)
[Boiling point ]

528.69°C (rough estimate)
[density ]

1.1283 (rough estimate)
[refractive index ]

1.4360 (estimate)
Hazard InformationBack Directory
[Originator]

Tiomesterone,Yick-Vik Chemicals and Pharmaceticals (H.K.) Ltd.
[Uses]

Tiomesterone is an anabolic steroid and a derivative of testosterone (T155000), the principal hormone of the testes, produced by the interstitial cells.
[Definition]

ChEBI: Tiomesterone is a 3-hydroxy steroid. It has a role as an androgen.
[Manufacturing Process]

4 g 17α-methyl-1,4,6-androstatriene-17β-ol-3-one are boiled in 12 ml thioacetic acid under reflux for 1.5 hours. This reaction mixture is thereafter concentrated in vacuum to dryness and the 1α,7α -diacetylthio-17β-hydroxy- 17-methylandrost-4-en-3-one is crystallized from the residue after treatment with methanol; melting point 202-204°C; [α]D = -74.6° (dioxane); λmax 237.5 nm.
[Therapeutic Function]

Anabolic
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