Identification | Back Directory | [Name]
1,4-Benzodioxin-2-carboxylic acid, 6-[(2R)-2-[[(2R)-2-(3-chlorophenyl)-2-hydroxyethyl]amino]propyl]-2,3-dihydro-, (2R)- | [CAS]
220475-76-3 | [Synonyms]
N5984 N 5984 N-5984 KRP204 KRP-204 KRP 204 1,4-Benzodioxin-2-carboxylic acid, 6-[(2R)-2-[[(2R)-2-(3-chlorophenyl)-2-hydroxyethyl]amino]propyl]-2,3-dihydro-, (2R)- | [Molecular Formula]
C20H22ClNO5 | [MDL Number]
MFCD11040816 | [MOL File]
220475-76-3.mol | [Molecular Weight]
391.85 |
Hazard Information | Back Directory | [Uses]
N-5984 (KRP-204) is a potent and selective agonist of β3-adrenergic receptor. N-5984 has the potential for developing as one of the clinically effective drugs for obesity and diabetes mellitus[1]. | [IC 50]
β-adrenoceptor | [References]
[1] Yanagisawa T, et al. Selectivity and potency of agonists for the three subtypes of cloned human beta-adrenoceptors expressed in Chinese hamster ovary cells. Tohoku J Exp Med. 2000;192(3):181-193. DOI:10.1620/tjem.192.181 |
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