2198483-40-6

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2198483-40-6 Structure

Chemical Properties	Back Directory
[density ] 1.267±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)
[pka] 5.05±0.10(predicted)

Hazard Information	Back Directory
[Uses] NLRP3-IN-29(Compound 5M) is an inhibitor of NLR family pyrin domain containing 3 (NLRP3). NLRP3-IN-29 has the potential for blood-brain barrier permeability and inflammation inhibition both in vivo and in vitro. NLRP3-IN-29 can be used for research on Alzheimer's disease[1].
[References] [1] Kim EY, et al. Structure-based design and synthesis of sulfonylureas as novel NLRP3 inhibitors for Alzheimer's disease. Bioorg Med Chem Lett. 2024 Jan 19;99:129622. DOI:10.1016/j.bmcl.2024.129622

2198483-40-6 suppliers list

Company Name:	Shanghai Chaolan Chemical Technology Center
Tel:	021-QQ：65489617 15618227136
Website:	www.atkchemical.com/

Company Name:	Suzhou Zhixin Biotechnology Co., Ltd.
Tel:	0512-65118909 18100677375
Website:	www.szzxbio.com/

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2922814-80-8 2997864-57-8

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