Identification | Back Directory | [Name]
4(1H)-Quinolinone, 3-acetyl-8-bromo-5-chloro-2-[[[4-[(trifluoromethyl)thio]phenyl]methyl]sulfinyl]- | [CAS]
2173505-97-8 | [Synonyms]
c-Myc inhibitor 8 4(1H)-Quinolinone, 3-acetyl-8-bromo-5-chloro-2-[[[4-[(trifluoromethyl)thio]phenyl]methyl]sulfinyl]- | [Molecular Formula]
C19H12BrClF3NO3S2 | [MOL File]
2173505-97-8.mol | [Molecular Weight]
538.79 |
Hazard Information | Back Directory | [Uses]
c-Myc inhibitor 8 (compound 56) is a c-Myc inhibitor. c-Myc inhibitor 8 effectively inhibits cell viability of a variety of cancer cells. c-Myc inhibitor 8 inhibits human prostate and lung cancer growth in mouse models. c-Myc inhibitor 8 can be used for cancer research[1]. | [in vivo]
c-Myc inhibitor 8 (10 mg/kg; intraperitoneal injection, 3 times a week, for 10 days) inhibits tumor growth of human NCI-H1299 lung cancer mouse models[1].
c-Myc inhibitor 8 (30 mg/kg; intraperitoneal injection, 2 times a week, for 13 days) inhibits tumor growth of human prostate DU 145 cancer mouse models[1]. | [References]
[1] Jeong, Kyung Chae, et al. Anticancer pharmaceutical composition. WO2018021849. 2018. |
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