Identification | Back Directory | [Name]
2-Propenoic acid, 3-[5'-[4-(diphenylamino)phenyl][2,2'-bithiophen]-5-yl]-, (2E)- | [CAS]
2138330-43-3 | [Synonyms]
Photosensitizer-2 (E)-3-(5′-(4-(diphenylamino)phenyl)-(2,2′-bithiophen)-5-yl)acrylic acid (E)-3-(5'-(4-(Diphenylamino)phenyl)-[2,2'-bithiophen]-5-yl)acrylic acid 2-Propenoic acid, 3-[5'-[4-(diphenylamino)phenyl][2,2'-bithiophen]-5-yl]-, (2E)- | [Molecular Formula]
C29H21NO2S2 | [MOL File]
2138330-43-3.mol | [Molecular Weight]
479.61 |
Hazard Information | Back Directory | [Uses]
Photosensitizer-2 (compound 1) is a organic D-π-A sensitizer against phototoxicity. Photosensitizer-2 contains an acrylic acid moiety that exerts high levels of phototoxicity. Photosensitizer-2 shows antitumor activity against HeLa cells, with IC50 values of 20.9 ± 4.5 μM (dark) and 0.046 ± 0.012 μM (irradiation), respectively[1]. | [References]
[1] Fuse S, Moriya W, Sato S, Nakamura H. Investigation into the influence of an acrylic acid acceptor in organic D-π-A sensitizers against phototoxicity. Bioorg Med Chem. 2020 Jul 1;28(13):115558. DOI:10.1016/j.bmc.2020.115558 |
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