| Identification | Back Directory | [Name]
.DELTA.2-trans Eicosenoic Acid | [CAS]
2127095-72-9 | [Synonyms]
Δ2-trans Eicosenoic Acid
.DELTA.2-trans Eicosenoic Acid | [Molecular Formula]
C20H38O2 | [MOL File]
2127095-72-9.mol | [Molecular Weight]
310.51 |
| Chemical Properties | Back Directory | [Boiling point ]
430.5±14.0 °C(Predicted) | [density ]
0.895±0.06 g/cm3(Predicted) | [solubility ]
Ethanol: 20 mg/ml; Ethanol:PBS (pH 7.2)(1:1): .5 mg/ml | [form ]
A crystalline solid | [pka]
4.79±0.10(Predicted) |
| Hazard Information | Back Directory | [Description]
Δ2-trans Eicosenoic acid is an α,β-unsaturated fatty acid that is a bi-product of the synthesis of Δ2-cis eicosenoic acid. Δ2-cis eicosenoic acid and its salts have potential medical use for treating diabetes and improving lipid metabolism. A related compound, 2-octadecenoic acid, has been shown to improve liver function and decrease blood sugar in streptozocin-induced diabetic rats.1 | [Uses]
(2E)-Eicosenoic acid is an inhibitor of Mycobacterium tuberculosis protein tyrosine phosphatase A (PtpA). (2E)-Eicosenoic acid exhibits strong inhibitory activity against PtpA with an IC50 value in the low micromolar range. (2E)-Eicosenoic acid can be used for research on Mycobacterium tuberculosis infection[1]. | [Definition]
ChEBI: Trans-2-icosenoic acid is an icosenoic acid in which the double bond is at the 2-3 position and has E configuration. It is an icosenoic acid and an alpha,beta-unsaturated monocarboxylic acid. | [References]
1. Iwamura, J., Hayashi, C., and Nozomu, T. Medicinal use of α,β-unsaturated fatty acids App. 377,407,1-5(1984). |
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