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ChemicalBook--->CAS DataBase List--->2125724-72-1

2125724-72-1

2125724-72-1 Structure

2125724-72-1 Structure
IdentificationBack Directory
[Name]

WNK inhibitor 7
[CAS]

2125724-72-1
[Synonyms]

WNKIN7
WNK-IN-7
WNK IN 7
WNK inhibitor 7
[Molecular Formula]

C26H29N3O
[MOL File]

2125724-72-1.mol
[Molecular Weight]

399.53
Chemical PropertiesBack Directory
[Boiling point ]

573.3±50.0 °C(Predicted)
[density ]

1.10±0.1 g/cm3(Predicted)
[form ]

Solid
[pka]

9.86±0.29(Predicted)
[color ]

White to off-white
Hazard InformationBack Directory
[Description]

WNK-IN-7 is a potent and selectiive inhibitor of WNK1 kinase.
[Uses]

WNK-IN-1 (compound 7) is a ATP noncompetitive With-No-Lysine (WNK) kinase inhibitor (IC50=95 nM). WNK-IN-1 can be used to regulate cardiovascular homeostasis[1].
[References]

[1] Yamada K, et al. Optimization of Allosteric With-No-Lysine (WNK) Kinase Inhibitors and Efficacy in Rodent Hypertension Models. J Med Chem. 2017 Aug 24;60(16):7099-7107. DOI:10.1021/acs.jmedchem.7b00708
2125724-72-1 suppliers list
Company Name: TargetMol Chemicals Inc.
Tel: +17819995354 , +17819995354
Website: www.targetmol.com/
Company Name: TargetMol Chemicals Inc.
Tel: +17819995354 , +17819995354
Website:
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Website: https://www.targetmol.cn/
Company Name: Nanjing Shizhou Biology Technology Co.,Ltd  
Tel: 025-85560043 15850508050
Website: http://www.synzest.com
Tags:2125724-72-1 Related Product Information
2123483-49-6 853298-47-2 2123489-30-3

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