| Identification | Back Directory | [Name]
5-[(4S)-5-Acetyl-1,2,3,4-tetrahydro-6-methyl-2-oxo-1-[3-(trifluoromethyl)phenyl]-4-pyrimidinyl]-2-pyridinecarbonitrile | [CAS]
2117404-84-7 | [Synonyms]
5-[(4S)-5-Acetyl-1,2,3,4-tetrahydro-6-methyl-2-oxo-1-[3-(trifluoromethyl)phenyl]-4-pyrimidinyl]-2-pyridinecarbonitrile
2-Pyridinecarbonitrile, 5-[(4S)-5-acetyl-1,2,3,4-tetrahydro-6-methyl-2-oxo-1-[3-(trifluoromethyl)phenyl]-4-pyrimidinyl]- | [Molecular Formula]
C20H15F3N4O2 | [MDL Number]
MFCD31579863 | [MOL File]
2117404-84-7.mol | [Molecular Weight]
400.35 |
| Chemical Properties | Back Directory | [Boiling point ]
623.9±55.0 °C(Predicted) | [density ]
1.42±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO:45.02(Max Conc. mg/mL);112.45(Max Conc. mM) | [form ]
Solid | [pka]
9.35±0.70(Predicted) | [color ]
Light yellow to yellow | [optical activity]
[α]/D -21 to -29°, c =0.5 in methanol |
| Hazard Information | Back Directory | [Biological Activity]
BAY-677 is the negative control probe for BAY-678which is a human neutrophil elastase (HNE) inhibitor with >2,000-fold selectivity for HNE over a panel of 21 other serine proteases. For characterization details of BAY-678 and BAY-677please visit the BAY-677 probe summary on the Structural Genomics Consortium (SGC) website.
BAY-678the active HNE probeis available from Sigma. To learn more about and purchase BAY-678click here.
To learn about other SGC chemical probes for protein targetsvisit sigma.com/sgc | [storage]
Store at -20°C |
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BOC Sciences
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InvivoChem
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