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ChemicalBook--->CAS DataBase List--->2097787-75-0

2097787-75-0

2097787-75-0 Structure

2097787-75-0 Structure
IdentificationBack Directory
[Name]

Nur77 modulator 3
[CAS]

2097787-75-0
[Synonyms]

Nur77 modulator 3
Chemical PropertiesBack Directory
[form ]

Solid
[color ]

White to off-white
Hazard InformationBack Directory
[Uses]

Nur77 modulator 3 (9e) can bind to Nur77 and inhibit TGF-β1-induced α-SMA and COLA1 expression in a Nur77-dependent manner. Nur77 modulator 3 induces Nur77 expression and enhances autophagic flux by inhibiting the mTORC1 signaling pathway in vitro and in vivo. Nur77 modulator 3 blocks the progression of hepatic fibrosis[1].
[References]

[1] Lin G, et al. Identification of (E)-1-((1H-indol-3-yl)methylene)-4-substitute-thiosemicarbazones as potential anti-hepatic fibrosis agents. Bioorg Chem. 2023 Dec 16;143:107022. DOI:10.1016/j.bioorg.2023.107022
2097787-75-0 suppliers list
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