| Identification | Back Directory | [Name]
Hexanoic acid, 3-methyl-6-[2-[[5-methyl-2-[4-(trifluoromethyl)phenyl]-1H-imidazol-1-yl]methyl]phenoxy]-, (3R)- | [CAS]
2095128-20-2 | [Synonyms]
Bocidelpar
Hexanoic acid, 3-methyl-6-[2-[[5-methyl-2-[4-(trifluoromethyl)phenyl]-1H-imidazol-1-yl]methyl]phenoxy]-, (3R)-
peroxisome proliferator-activated receptor delta,Inhibitor,inhibit,Peroxisome proliferator-activated receptors,PPAR,Duchenne Muscular Dystrophy,PPAR-δ,mitochondrial biogenesis,Bocidelpar,DMD | [Molecular Formula]
C25H27F3N2O3 | [MOL File]
2095128-20-2.mol | [Molecular Weight]
460.49 |
| Chemical Properties | Back Directory | [Boiling point ]
613.4±65.0 °C(Predicted) | [density ]
1.21±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO : 250 mg/mL (542.90 mM; Need ultrasonic) | [form ]
Solid | [pka]
4.76±0.10(Predicted) | [color ]
Off-white to light yellow |
| Hazard Information | Back Directory | [Uses]
Bocidelpar is a modulator of peroxisome proliferator-activated receptor delta (PPAR-δ). Bocidelpar improves mitochondrial biogenesis and function in Duchenne Muscular Dystrophy (DMD) muscle cells[1][2]. | [storage]
Store at -20°C | [References]
[1] Michael Downes, et al. Ppar agonists, compounds, pharmaceutical compositions, and methods of use thereof. Patent WO2017062468A1.
[2] Ito M, et al. Single- and multiple-dose safety, tolerability, pharmacokinetic, and pharmacodynamic profiles of ASP0367, or bocidelpar sulfate, a novel modulator of peroxisome proliferator-activated receptor delta in healthy adults: Results from a phase 1 study. Muscle Nerve. 2022 Jan;65(1):110-120. DOI:10.1002/mus.27436 |
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| Company Name: |
BOC Sciences
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| Tel: |
1-631-485-4226; 16314854226 |
| Website: |
https://www.bocsci.com |
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