| Identification | Back Directory | [Name]
N-Boc-N-bis(PEG4-NHS ester) | [CAS]
2093153-08-1 | [Synonyms]
N-Boc-N-bis(PEG4-NHS ester)
3,6,9,12,18,21,24,27-Octaoxa-15-azanonacosane-1,15,29-tricarboxylic acid, 15-(1,1-dimethylethyl) 1,29-bis(2,5-dioxo-1-pyrrolidinyl) ester | [Molecular Formula]
C35H57N3O18 | [MDL Number]
MFCD29912670 | [MOL File]
2093153-08-1.mol | [Molecular Weight]
807.836 |
| Hazard Information | Back Directory | [Description]
N-Boc-N-bis(PEG4-NHS ester) is a branched PEGylation reagent. The NHS esters can be used to label proteinsor other amine-attached molecules. Boc can be removed under acidic conditions. | [Uses]
N-Boc-N-bis(PEG4-NHS ester) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | [IC 50]
PEGs; Alkyl/ether | [References]
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
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