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ChemicalBook--->CAS DataBase List--->2055050-87-6

2055050-87-6

2055050-87-6 Structure

2055050-87-6 Structure
IdentificationBack Directory
[Name]

LAU159
[CAS]

2055050-87-6
[Synonyms]

LAU159
CS-2770
LAU159;LAU-159;LAU 159
8-Chloro-2,5-dihydro-2-(3-methoxyphenyl)-3H-pyrazolo[4,3-c]quinolin-3-one
3H-Pyrazolo[4,3-c]quinolin-3-one, 8-chloro-2,5-dihydro-2-(3-methoxyphenyl)-
[Molecular Formula]

C17H12ClN3O2
[MDL Number]

MFCD31922710
[MOL File]

2055050-87-6.mol
[Molecular Weight]

325.75
Chemical PropertiesBack Directory
[Boiling point ]

473.8±55.0 °C(Predicted)
[density ]

1.45±0.1 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

DMSO: soluble
[form ]

A crystalline solid
[pka]

6.26±0.20(Predicted)
Hazard InformationBack Directory
[Uses]

LAU159 is a functionally selective positive modulator of α1β3 GABA(A) receptor with an EC50 of 2.2 μM[1].
[References]

[1] Varagic Z, et al. Identification of novel positive allosteric modulators and null modulators at the GABAA receptor α+β- interface. Br J Pharmacol. 2013 May;169(2):371-83. DOI:10.1111/bph.12151
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