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ChemicalBook--->CAS DataBase List--->2042211-13-0

2042211-13-0

2042211-13-0 Structure

2042211-13-0 Structure
IdentificationBack Directory
[Name]

Mcl1-IN-11
[CAS]

2042211-13-0
[Synonyms]

Mcl1-IN-11
Mcl1 IN 11,Mcl-1-IN-11,Mcl1IN11
[Molecular Formula]

C38H41N3O5S2
[MDL Number]

MFCD32174235
[MOL File]

2042211-13-0.mol
[Molecular Weight]

683.88
Chemical PropertiesBack Directory
[density ]

1.30±0.1 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

Soluble in DMSO
[pka]

4.26±0.10(Predicted)
Hazard InformationBack Directory
[Description]

Mcl1-IN-11 (Compound G) is a selective Mcl-1 inhibitor, less potent at Bcl-2, with Kis of 0.06 and 4.2 μM, respectively[1]. Ki: 0.06 (Mcl-1), 4.2 μM (Bcl-2)[1]

[Uses]

Mcl1-IN-11 (Compound G) is a selective Mcl-1 inhibitor, less potent at Bcl-2, with Kis of 0.06 and 4.2 μM, respectively[1].
[References]

[1]. Wang M, et al. Design, synthesis, and activity evaluation of selective inhibitors of anti-apoptotic Bcl-2 proteins: The effects on the selectivity of the P1 pockets in the active sites. Bioorg Med Chem Lett. 2016 Nov 1;26(21):5207-5211.

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