Identification | Back Directory | [Name]
BAY-27-9955 | [CAS]
202855-56-9 | [Synonyms]
BAY-27-9955 BAY279955,BAY 27 9955 [1,1'-Biphenyl]-2-methanol, 4'-fluoro-α-methyl-3,5-bis(1-methylethyl)-6-propyl-, (+)- | [Molecular Formula]
C23H31FO | [MOL File]
202855-56-9.mol | [Molecular Weight]
342.5 |
Hazard Information | Back Directory | [Uses]
BAY-27-9955 is an orally active non-peptide glucagon receptor antagonist. Bay 27-9955 competitively blocks the interaction of glucagon with the human glucagonreceptor at an IC50 value of 110 nM. BAY-27-9955 can be used for the study of type 2 diabetes[1]. | [References]
[1] K F Petersen, et al. Effects of a novel glucagon receptor antagonist (Bay 27-9955) on glucagon-stimulated glucose production in humans. Diabetologia. 2001 Nov;44(11):2018-24. DOI:10.1007/s001250100006 |
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