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ChemicalBook--->CAS DataBase List--->202855-56-9

202855-56-9

202855-56-9 Structure

202855-56-9 Structure
IdentificationBack Directory
[Name]

BAY-27-9955
[CAS]

202855-56-9
[Synonyms]

BAY-27-9955
BAY279955,BAY 27 9955
[1,1'-Biphenyl]-2-methanol, 4'-fluoro-α-methyl-3,5-bis(1-methylethyl)-6-propyl-, (+)-
[Molecular Formula]

C23H31FO
[MOL File]

202855-56-9.mol
[Molecular Weight]

342.5
Chemical PropertiesBack Directory
[Boiling point ]

446.1±45.0 °C(Predicted)
[density ]

1.008±0.06 g/cm3(Predicted)
[pka]

14.57±0.20(Predicted)
Hazard InformationBack Directory
[Uses]

BAY-27-9955 is an orally active non-peptide glucagon receptor antagonist. Bay 27-9955 competitively blocks the interaction of glucagon with the human glucagonreceptor at an IC50 value of 110 nM. BAY-27-9955 can be used for the study of type 2 diabetes[1].
[References]

[1] K F Petersen, et al. Effects of a novel glucagon receptor antagonist (Bay 27-9955) on glucagon-stimulated glucose production in humans. Diabetologia. 2001 Nov;44(11):2018-24. DOI:10.1007/s001250100006
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