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ChemicalBook--->CAS DataBase List--->20227-41-2

20227-41-2

20227-41-2 Structure

20227-41-2 Structure
IdentificationBack Directory
[Name]

9-(2-Deoxy-2-fluoro-beta-D-arabinofuranosyl)adenine
[CAS]

20227-41-2
[Synonyms]

2'-FANA-Ar
Ara-2'-F-2'-dA
-4-fluoro-2-(hydroxymethyl)
2'-Deoxy-2'-fluoroarabinoadenosine
2'-Deoxy-2'-fluoro-beta-D-arabinoadenosine
6-AMino-purine-2'-fluoro-2'-deoxy arabineoside
9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)adenine
9-(2'-Deoxy-2'-fluoro-b-D-arabinofuranosyl)adenine
9-(2-Deoxy-2-fluoro-beta-D-arabinofuranosyl)adenine
9-(2-Deoxy-2-fluoro-beta-D-arabinofuranosyl)-9H-purin-6-amine
(2R,3R,4S,5R)-5-(6-Amino-9H-purin-9-yl)-4-fluoro-2-(hydroxymethyl)tetrahydrofuran-3-ol
[Molecular Formula]

C10H12FN5O3
[MDL Number]

MFCD12911815
[MOL File]

20227-41-2.mol
[Molecular Weight]

269.23
Chemical PropertiesBack Directory
[Melting point ]

233-234 °C
[Boiling point ]

628.6±65.0 °C(Predicted)
[density ]

2.01
[form ]

Solid
[pka]

12.60±0.70(Predicted)
[color ]

White to off-white
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H315-H319-H335
[Precautionary statements ]

P261-P305+P351+P338
Hazard InformationBack Directory
[Uses]

2'-Deoxy-2'-fluoroarabinoadenosine is a nucleoside analogue, which exhibits anticancer activity against human immunodeficiency virus (HIV)[1].
[References]

[1] Marquez VE, et al., 2',3'-Dideoxy-2'-fluoro-ara-A. An acid-stable purine nucleoside active against human immunodeficiency virus (HIV). Biochem Pharmacol. 1987 Sep 1;36(17):2719-22. DOI:10.1016/0006-2952(87)90254-1
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