Identification | Back Directory | [Name]
CHRYSOERIOL-7-O-BETA-D-GLUCOSIDE | [CAS]
19993-32-9 | [Synonyms]
Termopsoside Thermopsoside Chrysoeriol-7-0-glucosid Chrysoeriol 7-O-glucosid Chrysoeriol 7-O-glucoside 7-O-(beta-D-Glucosyl)chrysoeriol CHRYSOERIOL-7-O-BETA-D-GLUCOSIDE Chrysoeriol-7-O-β-D-glucopyranoside Chrysoeriol 7-O-beta-glucopyranoside Chrysoeriol 7-O-beta-D-glucopyranoside CHRYSOERIOL-7-O-Β-D-GLUCOPYRANOSIDE; THERMOPSOSIDE 4H-1-Benzopyran-4-one, 7-(β-D-glucopyranosyloxy)-5-hydroxy-2-(4-hydroxy-3-methoxyphenyl)- 5-hydroxy-2-(4-hydroxy-3-methoxyphenyl)-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-4-one | [EINECS(EC#)]
300-008-0 | [Molecular Formula]
C22H22O11 | [MDL Number]
MFCD11975476 | [MOL File]
19993-32-9.mol | [Molecular Weight]
462.4 |
Chemical Properties | Back Directory | [Melting point ]
176-179℃ | [Boiling point ]
801.6±65.0 °C(Predicted) | [density ]
1.609 | [solubility ]
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | [form ]
powder | [pka]
6.10±0.40(Predicted) | [color ]
Yellow |
Hazard Information | Back Directory | [Uses]
Thermopsoside is a flavone derivative isolated from Aspalathus linearis. Thermopsoside exhibits inhibitory effects on CYP450 isozymes with IC50 values of 6.0 μM, 9.5 μM, 12.0 μM, 32.0 μM, for CYP3A4, CYP2C19, CYP2D6 and CYP2C9, respectively[1]. | [References]
[1] Omer I Fantoukh, et al. Safety Assessment of Phytochemicals Derived from the Globalized South African Rooibos Tea ( Aspalathus linearis) through Interaction with CYP, PXR, and P-gp. J Agric Food Chem. 2019 May 1;67(17):4967-4975. DOI:10.1021/acs.jafc.9b00846 |
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