| Identification | Back Directory | [Name]
TRPA1 Antagonist 1 | [CAS]
1984825-08-2 | [Synonyms]
TRPA1 Antagonist 1
TRPA-1 Antagonist 1,TRPA1 Antagonist 1 | [Molecular Formula]
C24H23F6N5NaO7PS | [MDL Number]
MFCD31813644 | [MOL File]
1984825-08-2.mol | [Molecular Weight]
693.49 |
| Hazard Information | Back Directory | [Uses]
TRPA1 Antagonist 1 is a methylene phosphate proagent which converts to its active parent agent, a TRPA1 antagonist with an IC50 of 8 nM. | [References]
[1] Chen H, et al. Discovery of a Potent (4 R,5 S)-4-Fluoro-5-methylproline Sulfonamide Transient Receptor Potential Ankyrin 1 Antagonist and Its Methylene Phosphate Prodrug Guided by Molecular Modeling. J Med Chem. 2018 Apr 26;61(8):3641-3659. DOI:10.1021/acs.jmedchem.8b00117 |
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