| Identification | Back Directory | [Name]
BENZO(C)PHENANTHRENE | [CAS]
195-19-7 | [Synonyms]
195-19-7
Tetrahelicene
BENZO(C)PHENANTHRENE
3,4-Benzphenanthrene
3,4-Benzophenanthrene
Benzo-3,4-phenanthrene
3,4-Benzo[c]phenthrene
3,4-Benzo[c]phenanthrene
AR-G 3 BENZO(C)PHENANTHRENE
Benzo[c]phenanthrene (purity)
60624, Benzo[c]phenanthrene (purity)
Benzo(c)phenanthrene@50 μg/mL in Toluene | [EINECS(EC#)]
205-896-9 | [Molecular Formula]
C18H12 | [MDL Number]
MFCD00019126 | [MOL File]
195-19-7.mol | [Molecular Weight]
228.29 |
| Chemical Properties | Back Directory | [Melting point ]
158-160℃ | [Boiling point ]
305.1°C (rough estimate) | [density ]
1.1209 (estimate) | [refractive index ]
1.5500 (estimate) | [storage temp. ]
2-8°C | [solubility ]
Acetonitrile (Slightly), Chloroform (Slightly) | [form ]
neat | [color ]
Needles from EtOH or pet ether | [BRN ]
1909296 | [Stability:]
Light Sensitive | [InChI]
InChI=1S/C18H12/c1-3-7-16-13(5-1)9-11-15-12-10-14-6-2-4-8-17(14)18(15)16/h1-12H | [InChIKey]
TUAHORSUHVUKBD-UHFFFAOYSA-N | [SMILES]
C1=C2C(C3C(C=C2)=CC=CC=3)=C2C=CC=CC2=C1 | [IARC]
2B (Vol. 92, Sup 7) 2010 | [EPA Substance Registry System]
Benzo[c]phenanthrene (195-19-7) |
| Hazard Information | Back Directory | [Chemical Properties]
Yellow Solid | [Uses]
A PAH metabolite having a toxic effect on fish bone metabolite. Also, it is used as a marker of the carcinogenic potency of the polycyclic aromatic hydrocarbons (PAH) mixture. A genotoxic agent. | [Definition]
ChEBI: An ortho-fused polycyclic arene resulting from the symmetrical fusion of the C1-C2 bonds of two naphthalene units. | [Safety Profile]
Questionable carcinogen withexperimental tumorigenic data. Mutation data reported.When heated to decomposition it emits acrid and irritatingfumes. | [Carcinogenicity]
Dermal administration (initiation–
promotion protocols) to mice showed benzo[c]phenanthrene
was a tumor-initiating agent. Repeated dermal
administration in mice or subcutaneous injection into mice
or rats gave results considered to be inadequate for evaluation
(3). Intraperitoneal injection of benzo[c]phenanthrene
into infant mice resulted in a substantial induction of
lung tumors. Seven suspected activated metabolites were
also active, as well as in two-stage mouse carcinogenesis
assays. | [Purification Methods]
Crystallise benzo[c]phenanthrene from EtOH, pet ether, or EtOH/Me2CO. [Beilstein 5 III 2378, 5 IV 2552.] |
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