| Identification | Back Directory | [Name]
H-PRO-HYP-OH | [CAS]
18684-24-7 | [Synonyms]
Pro-Hyp
Dipeptide-6
H-PRO-HYP-OH
L-PRO-HYPRO-PRO
PRO-HYDROXY-PRO
Pro-Hyp zwitterion
Prolylhydroxyproline
Pro-Hyp-OH≥ 99% (TLC)
H-PRO-HYP-OH USP/EP/BP
L-Prolyl-L-hydroxyproline
4-Hydroxy-1-L-prolyl-L-proline
L-Proline, L-prolyl-4-hydroxy-, (4R)-
(2S,4R)-1-(L-prolyl)-4-hydroxypyrrolidine-2-carboxylic acid
4-hydroxy-1-[oxo(2-pyrrolidinyl)methyl]-2-pyrrolidinecarboxylic acid
(2S,4R)-4-hydroxy-1-((S)-pyrrolidine-2-carbonyl)pyrrolidine-2-carboxylic acid
(2S,4R)-4-hydroxy-1-[(2S)-pyrrolidine-2-carbonyl]pyrrolidine-2-carboxylic acid | [EINECS(EC#)]
-0 | [Molecular Formula]
C10H16N2O4 | [MDL Number]
MFCD00037349 | [MOL File]
18684-24-7.mol | [Molecular Weight]
228.25 |
| Chemical Properties | Back Directory | [Boiling point ]
513.5±50.0 °C(Predicted) | [density ]
1.417±0.06 g/cm3(Predicted) | [storage temp. ]
-15°C | [solubility ]
Aqueous Acid (Slightly), DMSO (Slightly), Methanol (Slightly) | [form ]
Solid | [pka]
2.98±0.40(Predicted) | [color ]
White to Off-White | [Stability:]
Hygroscopic |
| Hazard Information | Back Directory | [Chemical Properties]
White powder | [Uses]
H-Pro-Hyp-OH is a collagen peptide composed of proline (Pro) and hydroxyproline (Hyp). H-Pro-Hyp-OH can be used in research on slowing down facial aging[1]. | [Definition]
ChEBI: Pro-Hyp is a dipeptide composed of L-proline and L-hydroxyproline residues. It is a biomarker for bone collagen degradation. It has a role as a diagnostic agent, a human metabolite and a biomarker. It is functionally related to a L-proline and a trans-4-hydroxy-L-proline. It is a tautomer of a Pro-Hyp zwitterion. | [References]
[1] Tedesco L, et al. A designer mixture of six amino acids promotes the extracellular matrix gene expression in cultured human fibroblasts. Biosci Biotechnol Biochem. 2022 Aug 24;86(9):1255-1261. DOI:10.1093/bbb/zbac101 |
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