Identification | Back Directory | [Name]
CP-320626 | [CAS]
186430-23-9 | [Synonyms]
CP-320626 1H-Indole-2-carboxamide, 5-chloro-N-[(1S)-1-[(4-fluorophenyl)methyl]-2-(4-hydroxy-1-piperidinyl)-2-oxoethyl]- | [Molecular Formula]
C23H23ClFN3O3 | [MDL Number]
MFCD00954137 | [MOL File]
186430-23-9.mol | [Molecular Weight]
443.9 |
Hazard Information | Back Directory | [Uses]
CP320626 is a potent inhibitor of human liver glycogen phosphorylase (IC50=205 nM). CP320626 reduces blood glucose in diabetic mice without changing plasma insulin levels. CP320626 can be used in the study of type 2 diabetes[1]. | [References]
[1] Oikonomakos, et al. A new allosteric site in glycogen phosphorylase b as a target for drug interactions. Structure 8.6 (2000): 575-584. DOI:10.1016/s0969-2126(00)00144-1 |
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