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ChemicalBook--->CAS DataBase List--->186430-23-9

186430-23-9

186430-23-9 Structure

186430-23-9 Structure
IdentificationBack Directory
[Name]

CP-320626
[CAS]

186430-23-9
[Synonyms]

CP-320626
1H-Indole-2-carboxamide, 5-chloro-N-[(1S)-1-[(4-fluorophenyl)methyl]-2-(4-hydroxy-1-piperidinyl)-2-oxoethyl]-
[Molecular Formula]

C23H23ClFN3O3
[MDL Number]

MFCD00954137
[MOL File]

186430-23-9.mol
[Molecular Weight]

443.9
Chemical PropertiesBack Directory
[Boiling point ]

770.8±60.0 °C(Predicted)
[density ]

1.401±0.06 g/cm3(Predicted)
[pka]

14.06±0.46(Predicted)
Hazard InformationBack Directory
[Uses]

CP320626 is a potent inhibitor of human liver glycogen phosphorylase (IC50=205 nM). CP320626 reduces blood glucose in diabetic mice without changing plasma insulin levels. CP320626 can be used in the study of type 2 diabetes[1].
[References]

[1] Oikonomakos, et al. A new allosteric site in glycogen phosphorylase b as a target for drug interactions. Structure 8.6 (2000): 575-584. DOI:10.1016/s0969-2126(00)00144-1
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