| Identification | Back Directory | [Name]
4',5'-Didehydro-5'-deoxy-2'-O-methyluridine | [CAS]
1848223-48-2 | [Synonyms]
4',5'-Didehydro-5'-deoxy-2'-O-methyluridine
5'-Deoxy-4',5'-didehydro-2'-O-methyluridine
4’,5’-Didehydro-5’-deoxy-2’-O-methyluridine
Uridine, 4',5'-didehydro-5'-deoxy-2'-O-methyl-
5'-?Deoxy-?4',?5'-?didehydro-?2'-?O-?methyluridine | [Molecular Formula]
C10H12N2O5 | [MOL File]
1848223-48-2.mol | [Molecular Weight]
240.21 |
| Hazard Information | Back Directory | [Uses]
4′,5′-Didehydro-5′-deoxy-2′-O-methyluridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. | [References]
[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005 |
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