午夜插插,噜噜噜影院,啪啪伊人网,欧美熟夫,景甜吻戏视频,男人强操性感蕾丝美女视频在线网站,日本美女跳舞视频

ChemicalBook--->CAS DataBase List--->1810710-59-8

1810710-59-8

1810710-59-8 Structure

1810710-59-8 Structure
IdentificationBack Directory
[Name]

PCTR1
[CAS]

1810710-59-8
[Synonyms]

PCTR1
[Molecular Formula]

C32H47N3O9S
[MOL File]

1810710-59-8.mol
[Molecular Weight]

649.8
Chemical PropertiesBack Directory
[storage temp. ]

Store at -20°C
[solubility ]

DMF: 50 mg/ml; DMSO: 50 mg/ml; Ethanol: 1 mg/ml; Ethanol/H20 (95:5): 2 mg/ml; PBS (pH 7.2): 0.1 mg/ml
Safety DataBack Directory
[Symbol(GHS) ]


GHS02,GHS07
[Signal word ]

Danger
[Hazard statements ]

H225-H319
[Precautionary statements ]

P210-P233-P240-P241-P242-P243-P264-P280-P303+P361+P353-P305+P351+P338-P337+P313-P370+P378-P403+P235-P501
Hazard InformationBack Directory
[Description]

Protectin conjugates in tissue regeneration 1 (PCTR1) is a specialized pro-resolving mediator (SPM) synthesized from docosahexaenoic acid (DHA; ).1 DHA is oxidized to 16S,17S-epoxy-protectin, which is then converted to PCTR1 by glutathione S-transferase.1,2 PCTR1 levels increase during resolution of acute microbial-induced peritonitis in mice.3 PCTR1 (30 ng, i.p.) administration 12 hours post-infection increases macrophage numbers and activity and shortens the resolution phase of inflammation by 57%. It also reduces the levels of PGE2 , PGD2 , and TXB2 in peritoneal exudates.
[Uses]

PCTR1 is a potent monocyte/macrophage agonist, regulating key anti-inflammatory and pro-resolving processes during bacterial infection. PCTR1 is a member of the protectin family of specialized pro-resolving mediators (SPMs)[1].
[in vivo]

PCTR1, a lipid mediator, exerts fundamental anti-inflammation and pro-resolution during infection[3].
PCTR1 (50?ng/mice) improves the survival rate in an LPS-induced acute inflammatory mouse model[3].

Animal Model:C57BL/6J wild-type male mice (8-10 weeks old, 22-25?g)[3]
Dosage:50?ng/mice
Administration:Administered via the tail vein 1?h after LPS (15?mg/kg) intraperitoneal injection. The survival rate was recorded every day for 7 days
Result:Compared with the LPS group, the survival rate was significantly higher in the LPS?+?PCTR1 group, indicating that PCTR1 markedly increases the survival rate.
[storage]

Store at -20°C
[References]

1. Rodriguez, A.R., and Spur, B.W. Total synthesis of pro-resolving and tissue-regenerative protectin sulfido-conjugates Tetrahedron Lett. 56(42),5811-5815(2015).
2. Aursnes, M., Tungen, J.E., Colas, R.A., et al. Synthesis of the 16S,17S-epoxyprotectin intermediate in the biosynthesis of protectins by human macrophages J. Nat. Prod. 8(12),2924-2931(2015).
3. Ramon, S., Dalli, J., Sanger, J.M., et al. The protectin PCTR1 is produced by human M2 macrophages and enhances resolution of infectious inflammation Am. J. Pathol. 186(4),962-973(2016).
1810710-59-8 suppliers list
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354; +17819995354 , +17819995354
Website: https://www.targetmol.com/
Company Name: Shanghai EFE Biological Technology Co., Ltd.  
Tel: 021-65675885 18964387627
Website: http://www.efebio.com
Company Name: Shanghai Hongye Biotechnology Co. Ltd  
Tel: 400-9205774
Website: www.glpbio.cn
Company Name: ChemeGen(Shanghai) Biotechnology Co.,Ltd.  
Tel: 18818260767
Website: http://www.chemegen.com
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Website: https://www.targetmol.cn/
Company Name: Cayman Chemical Company  
Tel: 800-364-9897
Website: www.caymanchem.com
Company Name: Biosynth Biological Technology (Suzhou) Co Ltd  
Tel: 51288865780
Website: www.biosynth.com
Company Name: Neobioscience Co., Ltd.  
Tel: 4006-800-892
Website: www.nbs-bio.com
Company Name: Cayman Chemical Company  
Tel: (800) 364-9897
Website: www.caymanchem.com
Company Name: Shanghai Hao Zhun Biological Technology Co., Ltd.  
Tel: 15800340161
Website: www.zzsrm.com
Tags:1810710-59-8 Related Product Information

  • HomePage | Member Companies | Advertising | Contact us | Previous WebSite | MSDS | CAS Index | CAS DataBase | Privacy | Terms | About Us
  • All products displayed on this website are only for non-medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.
    According to relevant laws and regulations and the regulations of this website, units or individuals who purchase hazardous materials should obtain valid qualifications and qualification conditions.
  • Copyright © 2023 ChemicalBook All rights reserved.